Prof. Helen Coleman
Professor of Cancer Epidemiology, Centre for Public Health, Queen's University Belfast
Professor Helen Coleman is Lead of the Cancer Epidemiology Research Group at the Centre for Public Health at Queen’s University Belfast.
She has published over 90 peer-reviewed articles on the epidemiology of gastrointestinal cancers and pre-malignant conditions, with particular interests in Barrett’s oesophagus and oesophageal adenocarcinoma, colorectal polyps and colorectal cancer.
In addition to mainstay interests in the role of modifiable risk factors (such as smoking, alcohol and nutrition) in cancer risk and progression, she had specialist interests in clinical epidemiology related to gastrointestinal pathology diagnosis trends and concordance, and molecular pathology epidemiology.
Professor Coleman has over 10 years of experience working with the population-based Northern Ireland Barrett’s register, which is housed within the Northern Ireland Cancer Registry. She has also conducted many systematic reviews of lifestyle factors and biomarkers in cancer risk and progression.
Professor Coleman is affiliated to the Centre for Cancer Research and Cell Biology at Queen’s University Belfast, and is currently a Visiting Scientist with the Fitzgerald Lab at the MRC Cancer Unit, Cambridge, to further enhance interdisciplinary research efforts in oesophageal cancer as part of a Cancer Research UK funded Career Establishment Award (2018-2024).
Title: ‘Insights from Molecular Pathology Epidemiology studies of Oesophageal and Colorectal Neoplasia’
Summary: This talk will outline the application of molecular pathology epidemiology (MPE) studies to gastrointestinal neoplasia progression.
MPE studies investigate the interaction between biomarkers and epidemiological risk factors to better understand why some patients with pre-malignant conditions of the gastrointestinal tract develop cancer, and how these may interact to influence survival following a cancer diagnosis.
Professor Coleman will outline her current research from Cancer Research UK and other funded MPE studies of oesophageal and colorectal neoplasia progression.
This includes findings from a large inter-disciplinary cohort of 700 population-representative Stage II and III colon adenocarcinoma patients diagnosed between 2004-2008 in Northern Ireland, and new research within the UK OCCAMS consortium of over 3,000 oesophageal cancer patients.
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