Professor Alessandra Gennari

Professor Alessandra Gennari

Associate Professor of Oncology at the University of Eastern Piedmont (UPO) Head of the Division of Oncology at Maggiore Hospital, Novara, IT. Head of the Laboratory of Immuno-Oncology at the UPO-CAAD Center for Immune and Allergic Diseases, Novara, IT.

Dr Gennari’s areas of expertise include diagnostic and therapeutic innovation in breast cancer. Her current research is focused on the identification of individual drug responsiveness in breast tumors and therapy optimization in metastatic breast cancer. Other active research areas include the evaluation of host metabolism in breast cancer, functional imaging by PET-CT with 18F-FES to evaluate endocrine responsiveness in triple negative advanced breast cancer and identification of predictive factors of responsiveness to immunotherapy in advanced breast cancer.

She is the PI and Coordinator of the ERA-NET JTC 2011 project (European TRANSCAN project) – Early prediction of efficacy of endocrine therapy in breast cancer: pilot study and validation with 18F Fluoroestradiol (ET-FES project). She is also expanding research interests in immunotherapy and response prediction in BC. She acts as referee for numerous high-profile oncology journals, and has authored more than 90 peer-reviewed publications as well as numerous book chapters, abstracts, and other articles.

She is member of ASCO, ESMO and AIOM. She has served as international reviewer for the French National Cancer Institute (INCA), France (2010-2013). She is member of the Editorial Team (Clinical Editor) of the Cochrane Breast Cancer Group. From 2014 to 2018 she has been member of the Technical Scientific Committee (CTS) of IRCCS AZIENDA OSPEDALIERA UNIVERSITARIA SAN MARTINO IST, Genova, IT. She is member of the ABC (Advanced Breast Cancer) International Consensus Panel. – ESMO faculty member for the Breast cancer faculty group since 2017. She has served as Chair or Co-Chair of symposia in international conferences, organized by ESMO, ECCO and EBCC.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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Latest News

PhD in Tumour Immunology

A fully funded 4-year PhD studentship (€18,000 per annum stipend) is available in the research group of Dr. Aideen Ryan.

Education Grant 2020

The Irish Association for Cancer Research supported five Educational Grants in 2020. These were made available to postgraduate PhD researchers who had been affected by the Covid-19
 pandemic. 

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