Prof. Laurence Zitvogel

Prof. Laurence Zitvogel

Group Leader of Tumour immunology and immunotherapy of cancer, Institut Gustave Roussy

Pr L. Zitvogel, MD (clinical oncology), PhD (tumor immunology), PU-PH University Paris Saclay (Clinical Biology), graduated in Medical Oncology in 1992.

She started her scientific career when she was at the University of Pittsburgh, US. She became Research Director at Institut National de la Santé et Recherche Médicale U1015, and Scientific Director of the Immuno-Oncology program at Gustave Roussy, the largest cancer Center in Europe.

She has been actively contributing to the field of cancer immunology and immunotherapy. She pioneered the concept of immunogenic cell death and and discovered the critical impact of gut microbiota in cancer immunosurveillance and therapies.

She was the recipient of many awards including the French National Academy of Medicine, the Translation Research INSERM Prize, the ASCO-SITC, the Brupbacher Awards 2017, the ESMO Immuno-Oncology Award 2017, the Baillet Latour Prize 2019 and the Griffuel Prize 2019.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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