Prof. John Crown

Prof. John Crown

Consultant Medical Oncologist, St Vincent's University Hospital, Dublin, Ireland

Professor John Crown received his medical training in Ireland, the United Kingdom and the United States. He undertook his postdoctoral training in Guy’s Hospital, London and St. James’s Hospital, Dublin and went on to complete his fellowship training in oncology at Mount Sinai Medical Centre and at Memorial Sloan Kettering Cancer Centre. He served as Assistant Professor at Weill Cornell Medical College and Assistant Member at Memorial Sloan Kettering Cancer Centre before joining St Vincent’s University Hospital, Dublin, Ireland in 1993.

Professor Crown is a founding member and leader of many organisations, including: the All-Ireland Cooperative Oncology Research Group (ICORG, www.icorg.ie) and the Anglo-Celtic Cooperative Oncology Group (ACCOG). Prof Crown also founded the Clinical Trials Unit at St. Vincent’s University Hospital which has developed an international leadership role in oncology trials.

In 2008, Prof Crown was awarded a Health Research Board, Clinician Scientist Award which provided protected time for research. In 2009, he was awarded €5.6 million funding from Science Foundation Ireland, to establish a Strategic Research Cluster entitled Molecular Therapeutics for Cancer Ireland (MTCI). MTCI is a multi-institutional, translationally-focused laboratory based cancer research group which spans four academic and nine industrial partners. The focus of the research programme was to develop novel targeted therapies for breast and prostate cancer, encompassing the various stages of drug development from target identification, to preclinical evaluation of compounds (from industry partners), investigating mechanisms of response/resistance and ultimately to clinical trials, in collaboration with ICORG. Prof Crown is also Co-Director of the Irish Cancer Society funded Breast Predict Collaborative Cancer Research Centre (2013-2018) (www.breastpredict.com). He holds professorships in cancer research from both Dublin City University and University College Dublin.

Prof Crown has lectured in more than 40 countries and has received several national and international awards. He has published over 200 research articles.
From 2011 to 2016, Professor Crown served as an independent member of the Irish Senate (Seanad Eireann).

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

IACR 2023 Carer’s Bursary €300

Apply for funding towards additional costs of care while attending conference. Five Bursaries Available. 

Registration/ Membership for IACR 2023

Registration for the 59th Annual Conference in the Radisson Blu hotel, Athlone is Now Open.

EACR Membership is Included

The IACR is an affiliated national society and its members benefit from full membership of the EACR.

Biomedical Session Abstracts

Deadline: Midnight, Friday, 20th January 2023

Please note:
- Patrick Johnston Lay submission category is now closed
- Late Breaking Abstracts submitted to the Biomedical Sessions will be considered for Display Poster Presentation. 

Social Nursing and Allied Health (SNAH) Abstracts

Deadline: Midnight, Monday, 9th January 2023

SNAH abstract submissions will remain open until Monday 9th January.

Any questions?
Please contact Sinead on: sinead@sineadcassidy.com

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