Prof. Johanna Joyce

Prof. Johanna Joyce

Professor at the University of Lausanne, Switzerland, and Full Member of the international Ludwig Institute of Cancer Research.

Johanna Joyce is a Professor at the University of Lausanne, Switzerland, and Full Member of the international Ludwig Institute of Cancer Research.  Her laboratory investigates the microenvironment in which a tumour arises and the critical influence that non-cancerous immune and stromal cells can have on tumour progression, metastasis and therapeutic response.  

They have uncovered regulatory signals provided by the normal tissue stroma and immune cells to the cancer cells, and determined how normal cells can be modified by the cancer cells to produce a variety of factors that enhance tumor malignancy.  A major focus of the lab’s recent research has been to deeply and comprehensively interrogate the immune landscape of brain tumours, and then use this gained knowledge to develop novel strategies to therapeutically target the tumour microenvironment.

Prof. Joyce has been recognized for her contributions to cancer research through a series of awards including the Robert Bing Prize, Cloetta Prize, Swiss Bridge Award, American Cancer Society Scholar Award, Rita Allen Foundation Award, V Foundation Award, Sidney Kimmel Foundation Award, and many others.  She is a Member of EMBO, a Fellow of the European Academy of Cancer Sciences, and serves as the inaugural Executive Director of the Agora Cancer Centre Lausanne. She is originally from Ireland, and received her B.A. degree.in Genetics from Trinity College Dublin.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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