Prof. Jacintha O'Sullivan

Prof. Jacintha O'Sullivan

Professor in Translational Oncology, Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin

Prof. Jacintha O’Sullivan is a Professor in Translational Oncology and Education Director based at the Trinity St. James’s Hospital Cancer Institute. She is internationally recognised in the area of translational gastrointestinal cancer work with many publications in high impact
journals. Her work has attracted funding from many different sources for example, Science Foundation Ireland, Health Research Board, Breakthrough Cancer Research, Irish Cancer Society, Irish Research Council, Enterprise Ireland and from many industry and charity
collaborators. She received the honour of college fellowship in 2019 for recognition of research excellence in her subject area and has served as external assessor for many Ph.D. students, taught courses, and grant reviews nationally and internationally. She has filed and published many patents to drive the innovation and commercialisation aspects to her research programme. In 2022, she received an innovation award for engagement in academic industry partnerships. She has graduated over 30 postgraduate Ph.D. and MD students and is passionate about career mentoring. She was awarded IRC Research Ally Award for recognition of excellence as a supervisor/mentor. She has also received in 2023 and 2024, an award for excellence in supervision of research students.

She utilises well established bio-banking structures to drive her GI translational research program. Prof. O’Sullivan’s current translational research themes include 1. Development of diagnostic platforms to stratify cancer risk and response to targeted therapies for gastrointestinal diseases. 2. Development of novel patented therapeutics and novel technologies to be used in the neoadjuvant and adjuvant treatment setting for gastrointestinal cancer patients (Pan GI) to boost treatment responses. 3. Elucidating how the tumour microenvironment cross talks to the immune system in GI patients. 4. Importance of metabolism, inflammation, and obesity in driving disease progression and in regulating
treatment response in GI diseases. The outputs of these translational themes will benefit patient care, treatment, and management for gastrointestinal diseased patients.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

IACR 2023 Carer’s Bursary €300

Apply for funding towards additional costs of care while attending conference. Five Bursaries Available. 

Registration/ Membership for IACR 2023

Registration for the 59th Annual Conference in the Radisson Blu hotel, Athlone is Now Open.

EACR Membership is Included

The IACR is an affiliated national society and its members benefit from full membership of the EACR.

Biomedical Session Abstracts

Deadline: Midnight, Friday, 20th January 2023

Please note:
- Patrick Johnston Lay submission category is now closed
- Late Breaking Abstracts submitted to the Biomedical Sessions will be considered for Display Poster Presentation. 

Social Nursing and Allied Health (SNAH) Abstracts

Deadline: Midnight, Monday, 9th January 2023

SNAH abstract submissions will remain open until Monday 9th January.

Any questions?
Please contact Sinead on: sinead@sineadcassidy.com

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