Dr Stephen Maher

Dr Stephen Maher

Senior Council Member

 

Stephen Maher graduated from RCSI in 2004 with a PhD in Oncology. Having spent 3 years as a visiting fellow at the National Cancer Institute in the USA, in 2007 he returned to Ireland and the Department of Surgery at Trinity College Dublin, St. James’s Hospital as a research fellow.

In 2010 he established his own group having secured an Irish Cancer Society Fellowship and several project grants, all in the area of radiation research. In 2012 Stephen moved to the University of Hull and Hull York Medical School as a senior lecturer where he led the Cancer Biology and Therapeutics lab.

During his time at Hull he gained teaching qualifications and is a fellow of the UK Higher Education Academy. He has successfully supervised 6 PhD students and has supervised and mentored a number of postdoctoral researchers. He has secured in excess of €2m in competitive research funding and is well published in the field of oesophageal cancer and therapeutics research. His current research interests include cellular mechanisms underpinning resistance to chemotherapy and radiotherapy, cell signalling, isogenic cell models and animal xenograft models, radiologic imaging, hypoxia research, drug delivery and microRNAs. In 2016 Stephen returned to TCD as the James Ussher Assistant Professor in Translational Oncology, where he leads the Cancer Chemoradiation Research Group.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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Education Grants

The Irish Association for Cancer Research will support a limited number of Educational Grants that
will be made available to postgraduate PhD researchers who have been affected by the Covid-19
pandemic. We acknowledge that many of our members have been significantly impacted by the
recent pandemic that may have affected their ability to continue and/or complete research projects.

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