Dr Sanjeev Gupta
Senior Council
Sanjeev graduated with a BSc from the Delhi University, in 1994. He completed MSc in Biochemistry from the Hamdard University in 1996. Dr. Gupta was conferred with a PhD in 2002 by the Jawaharlal Nehru University, New Delhi, India. Dr. Gupta did his postdoctoral training with Prof. Emad Alnemri, a world leader in the field of apoptosis. He was appointed as a Lecturer in Pathology in December 2010 and promoted to Associate Professor in 2022.
His research focuses on the role of microRNAs in determining cell fate during conditions of Endoplasmic Reticulum (ER) stress. ER dysfunction plays an important role in a range of diseases, including Alzheimer’s disease, Parkinson’s disease, diabetes, cardiovascular diseases and cancer. His team uses a combination of molecular cell biology, transcriptomics, proteomics and miRNA expression profiling techniques to address specific questions such as: is there a “tipping point” of ER stress beyond which the UPR switches from pro-survival to pro-death response? The regulation of ER stress response by miRNAs offers enormous opportunities both in basic cell biology and in potential clinical applications. Sanjeev leads a research team aiming to understand and overcome endocrine resistance in hormonal breast cancer. He co-leads the Nu-PREDICT team currently engaged in the development of a hand-held at home device that can be used to monitor changes in neutrophil counts. Sanjeev sits on the editorial board of several international journals and assessment panels of funding agencies. He has published widely in high impact journals and has been invited to deliver keynote seminars at several national and international meetings.
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