Dr Noel McCaffrey

Dr Noel McCaffrey

DCU

Noel McCaffrey is a sports and exercise medicine specialist. He developed and directed the Dublin City University-based MedEx programme over a 10 year and has now left DCU to lead the national roll-out of this programme, rebranded as ExWell Medical. He graduated from UCD Medical School in 1983 and studied Sports Medicine in London 1986-88. He also worked in UCD Medical School from 1990-1996 developing and directing a new MSc Sports and Exercise Medicine Programme. He is a Foundation Fellow of the Faculty of Sports and Exercise Medicine, director of a private sports injury clinic and also runs a musculoskeletal injury clinic in Cappagh National Orthopaedic Hospital. ExWell Medical offers supervised exercise programmes to patients with diverse chronic illnesses on referral from health care professionals. A key component of the MedEx Service is exercise for cancer patients at all phases of the cancer journey.

Abstract:
COMMUNITY-BASED EXERCISE IN CANCER SURVIVORSHIP

Exercise has an important role in cancer management, at all stages of the cancer survivorship pathway. This paper will present the rationale for and experience of offering exercise programmes to 3 cancer cohorts over a period of 8 years. The first programme caters for people during or shortly after completing primary treatment (chemo-radiotherapy, surgery). The second offers intense exercise to patients preparing for (and recovering from) curative cancer surgery for diverse cancers, including colo-rectal, prostate, lung and oesophageal / upper GI). The third provides a gentle exercise offering for patients with advanced cancer. The challenges and benefits for each group are discussed and participant testimonials are presented. The core principles of the ExWell are community-based location, supervised and home options, group experience where possible, low tech approach to prescription, monitoring and outcomes and equity of access.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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Education Grant 2020

The Irish Association for Cancer Research supported five Educational Grants in 2020. These were made available to postgraduate PhD researchers who had been affected by the Covid-19
 pandemic. 

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