Dr Marion Butler
Senior Council Member
Dr Marion Butler was appointed as a lecturer in 2008 and currently leads a research group in the department of Biology at Maynooth University. Dr Butler’s research background is in immunology and cancer and her research is funded by the Health Research Board and the Irish Research Council. She previously held several post-doctoral research positions in University College Dublin and published in the areas of innate immune signalling and neuroimmunology.
In her position as principal investigator, she has returned to cancer research, where her expertise in immune signalling is now feeding into her research direction in cancer. She is collaborating with cancer researchers from several national universities and is focused on identifying novel targets involved in the progression of solid cancers including advanced prostate cancer and endocrine-resistant breast cancer.
3D mammosphere culture of breast epithelial cell line MCF10A.
Courtesy of Dr. Emer Bourke, NUI Galway.
Phospho-Akt expression and localisation
Mediated by VEGF in A549 lung cancer cells
Metaphase chromosome spread of Jurkat T-lymphoma cells
Apoptosis assessment of SKMES-1 lung cancer cells
Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).
Mitotic Chronic Myelogenous Leukaemia K562 Cells
Cell to Cell Tweeting
Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)
Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.
Confocal microscopy analysis
Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).
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