Dr Eva Szegezdi

Senior Council Member

Eva Szegezdi is a Research Lecturer in Cancer Biology and principal investigator at the Apoptosis Research Centre, National University of Ireland, Galway.

Dr. Szegezdi received her Ph.D. in medical science in 2000 studying cell death signalling at the University of Debrecen, Hungary. She joined the Cell Stress and Apoptosis Research laboratory led by Prof. Afshin Samali at the National University of Ireland, Galway in 2001 to study endoplasmic reticulum stress-induced cell death in heart and pancreatic cells and later death receptor signal transduction in cancer. She established her research group focusing on systems biology of death receptor signal transduction in cancer in 2010.

Current research in her laboratory focuses on signal transduction networks in cancer cells. Particular focus is the tumour-microenvironment in leukaemia and to identify a mechanism how the microenvironment can be altered to reject leukemic cells. Eva Szegezdi also acts as the founding director of Blood Cancer Biobank Ireland, director of the MSc programme in Cancer Research in NUIG and co-ordinator of the H2020-RISE programme, DISCOVER.

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3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

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Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

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