Dr Alex Eustace

Dr Alex Eustace

Senior Council Member

 

Dr Alex Eustace is the current Honorary Secretary of the Irish Association for Cancer Research.  Dr Eustace is an Assistant Professor at Dublin City University and a Principal Investigator in the National Institute for Cellular Biotechnology. Dr Eustace is also an award-winning translational oncology scientist who is a previous winner of the St Luke’s/ Royal Academy of Medicine Young Investigator award.

Dr Eustace’s lab primarily focuses on identifying and understanding the functional role of genetic vulnerabilities in cancer cells, which can then be exploited as novel treatment options for people who suffer with cancer. His research has directly led to the initiation of early phase clinical trials in both melanoma patients and women with HER2-positive breast cancer in Ireland. 

Dr Eustace has extensively researched the role of the PI3K/AKT signalling pathway and how it plays a role in making certain cancers more aggressive and harder to treat.  His lab aims to understand and exploit genetic alterations in this pathway to provide more specific treatments to treat these cancer patients.

3D mammosphere culture of breast epithelial cell line MCF10A.

Courtesy of Dr. Emer Bourke, NUI Galway

Phospho-Akt expression and localisation

Mediated by VEGF in A549 lung cancer cells. Visualised by high content image analysis.

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

Metaphase chromosome spread of Jurkat T-lymphoma cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Apoptosis assessment of SKMES-1 lung cancer cells

Using a multiparameter apoptosis staining kit, showing cell nuclei (blue), actin (green) and mitochondrial activity (orange).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

HeLa Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

IACR & EACR Joint Conference 2020

26 — 28 February 2020 at Galway Bay Hotel, Galway

Mitotic Chronic Myelogenous Leukaemia K562 Cells

Courtesy of Rebecca Gorry, PhD Student, Mc Gee Lab, UCD School of Biomolecular & Biomedical Science, Conway Institute, UCD

Cell to Cell Tweeting

Via nanoparticles (red) in Triple Negative Breast Cancer (TNBC)

Courtesy of Sinéad Lindsay, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD) Ireland.

Confocal Microscopy Analysis

Of phospho-Akt expression in H460 lung cancer cells in response to hypoxia (0.5% O2).

Courtesy of Dr Martin Barr, Clinical Scientist & Adjunct Assistant Professor, St James’s Hospital & Trinity College Dublin

EACR Free Membership

The IACR is an affiliated national society and its members benefit from full membership of the EACR.

Save The Date

IACR 2023 Conference
Venue: Athlone Radisson Blu Hotel
Dates:
Wed 22/02/2023 – Fri 24/02/2023

Please check back later in the year for more information.

IACR in the Irish Independent

We supported the Cancer 2022 Campaign from @Mediaplanet

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Irish Association for Cancer Research (IACR) is a registered charity on the Register of Charitable Organisations, Charities Regulator, 3 George's Dock, IFSC, Dublin 1, D01 X5X0, Ireland.

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